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Elizabeth Yuriev

Photo of Dr Yuriev

Lecturer

BSc, PhD (Victoria University), MRACI, ACS member, AMMA committee member (Association of the Molecular Modellers of Australasia – the Asia/Pacific Chapter of the Molecular Graphics and Modelling Society)

Phone: +61 3 9903 9611
Fax: +61 3 9903 9582
email: Elizabeth.Yuriev@pharm.monash.edu.au

Research Interests

  • Immunoglobulin cross-reactivity examined by library screening, crystallography and docking studies. Implications for rheumatoid arthritis
  • Collagen-induced arthritis: molecular modelling of anti-collagen antibody-peptide interactions
  • Investigation of steric aspects of metal complex interaction with nucleic acids
  • Steric aspects of nucleic acids recognition phenomena
  • Quantitative structure-activity relationships of sulfonamide- and imidazoline-based KATP channel blockers

Significant publications

  1. E. Yuriev, W. Farrugia, A. M. Scott, and P. A. Ramsland, "Three-dimensional Structures of Carbohydrate Determinants of Lewis System Antigens: Implications for Effective Antibody Targeting of Cancer", Immunology and Cell Biology, 2005, 83(6), 709-17.  (Invited review. Special Feature.) 
  2. E. Yuriev, D. C. Kong, and M. N. Iskander, "Investigation of Structure-Activity Relationships in a Series of Glibenclamide Analogues", European Journal of Medicinal Chemistry, 2004, 39, 835–847.
  3. P. A. Ramsland, W. Farrugia, E. Yuriev, A. B. Edmundson, and M. S. Sandrin, "Evidence for Structurally Conserved Recognition of the Major Carbohydrate Xenoantigen by Natural Antibodies", Cell Mol Biol (Noisy-le-grand), 2003, 49(2), 307-17. (Invited review.)
  4. [2,3-b][1,5]benzodiazepine Methanol Solvate Monohydrate", Acta Cryst., 2003, E59, o1367-o1369.
  5. V. Apostolopoulos, E. Yuriev, P. A. Ramsland, J. Halton, C. Osinski, W. Li, M. Plebanski, H. Paulsen, and I. F. C. McKenzie, "A glycopeptide in complex with MHC class I uses the GalNAc residue as an anchor", Proceedings of the National Academy of Sciences of the United States of America, 2003, 100, 15029-15034.
  6. E. Yuriev, P. A. Ramsland, and A. B. Edmundson, "Recognition of IgG-derived Peptides by a Human IgM with an Unusual Combining Site", Scandinavian Journal of Immunology 2002, 55(3), 242-253.
  7. and P. A. Ramsland, "Mcg Light Chain Dimer as a Model System for Ligand Design: A Docking Study", Journal of Molecular Recognition, 2002, 15(5), 331-340. (Invited contribution.)
  8. E. Yuriev, P. A. Ramsland, and A. B. Edmundson, "Docking of Combinatorial Peptide Libraries into a Broadly Cross-reactive Human IgM", Journal of Molecular Recognition, 2001, 14(3), 172-184.
  9. A. B. Edmundson, G. Tribbick, S. Plompen, H. M. Geysen, E. Yuriev, and P. A. Ramsland, "Binding of Synthetic Peptides by a Human Monoclonal IgM with an Unusual Combining Site Structure", Journal of Molecular Recognition, 2001, 14(4), 229-238.
  10. E. Yuriev, and A. B. Edmundson, "Immunoglobulin Cross-Reactivity Examined by Library Screening, Crystallography and Docking Studies", Combinatorial Chemistry and High Throughput Screening, 2001, 4(5), 397-408. (Invited review. This work is featured on the journal cover.)