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Martin J. Scanlon

Photo of Dr Martin Scanlon

Senior Lecturer

BSc Chemistry University of Leeds
MSc Medicinal Chemistry Loughborough University
PhD University of Nottingham

Phone: +61 3 9903 9540
Fax: +61 3 9903 9582
email: Martin.Scanlon@pharm.monash.edu.au

Research Experience

  • Biomolecular NMR spectroscopy
  • Structural Biology
  • Structure-based drug design
  • Fragment screening
  • Drug-protein binding

Significant Publications

  1. Gibbs, G.M., Scanlon, M.J., Swarbrick, J., Curtis, S., Gallant, E., Dulhunty, A.F. & O'Bryan, M.K. The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling. J Biol Chem 281, 4156-63 (2006).
  2. Perry, C.S., Charman, S.A., Prankerd, R.J., Chiu, F.C., Scanlon, M.J., Chalmers, D. & Charman, W.N. The binding interaction of synthetic ozonide antimalarials with natural and modified beta-cyclodextrins. J Pharm Sci 95, 146-58 (2006).
  3. Velkov, T., Chuang, S., Wielens, J., Sakellaris, H., Charman, W.N., Porter, C.J. & Scanlon, M.J. The interaction of lipophilic drugs with intestinal fatty acid-binding protein. J Biol Chem 280, 17769-76 (2005).
  4. Velkov, T., Chuang, S., Prankerd, R., Sakellaris, H., Porter, C.J. & Scanlon, M.J. An improved method for the purification of rat liver-type fatty acid binding protein from Escherichia coli. Protein Expr Purif 44, 23-31 (2005).
  5. Jennings, C.V., Rosengren, K.J., Daly, N.L., Plan, M., Stevens, J., Scanlon, M.J., Waine, C., Norman, D.G., Anderson, M.A. & Craik, D.J. Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do Mobius strips exist in nature? Biochemistry 44, 851-60 (2005).
  6. Shackleford, D.M., Prankerd, R.J., Scanlon, M.J. & Charman, W.N. Self-micellization of gemfibrozil 1-O-beta acyl glucuronide in aqueous solution. Pharm Res 20, 465-70 (2003).

Book Chapters

  1. Craik, D.J. & Scanlon, M.J. Two-, Three- and Four-Dimensional NMR of Biomolecules. in Encyclopedia of Analytical Chemistry (ed. Myers, R.A.) 12390-12411 (John Wiley and Sons, Chichester, 2000).
  2. Craik, D.J. & Scanlon, M.J. Pharmaceutical Applications of NMR. in Annual Reports on NMR Spectroscopy, Vol. 42 (ed. Webb, G.A.) 115-174 (Academic Press, 2000).