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Magdy N. Iskander

image of Magdy Iskander, Senior Lecturer, Medicinal Chemistry

Senior Lecturer

BSc., MSc., Alexandria University, Egypt, PhD., La Trobe University, Melbourne

Phone: +61 3 9903 9545
Fax: +61 3 9903 9582
email: Magdy.Iskander@pharm.monash.edu.au

Research Interests

  • Design, synthesis and MS-QSAR of enzymes inhibitors and receptor ligands.
  • Natural Products and Medicinal Plant-based drug Design and Development.

Significant Publications

  1. Yuriev, E.; Kong, D.; Iskander, M.. Investigation of structure-activity relationships in a series of glibenclamide analogues. J Bioorganic and Medicinal Chemistry. 2004. 39, 835-847.
  2. Islam, M. N.; Song, Y.; Iskander, M. Investigation of structural requirements of anticancer activity at the paclitaxel/tubulin binding site using CoMFA and CoMSIA.  J Computer-Aided Molecular Design. 2003. 21, 263-272.
  3. Parker, B. S.; Buley, T.; Evinson, B; Cutts, S. M.; Neumann, G. M.; Iskander, M. N.; Phillips, D. R. A molecular understanding of mitoxantrone-DNA adduct formation: Effect of cytosine methylation and flanking sequences. J Biolog, Chem. 2003.
  4. Islam, M. N.; Song, Y.; Iskander, M. N.  Investigation of structural requirements of anticancer activity at the paclitaxel/tubulin binding site using CoMFA and CoMSIA. J Computer-Aided molecular design. 2003. 21, 263-272.
  5. Iskander, M. N,: Coupar I. M.; Song, Y.  Anti-inflammatory activity of extracts and fractions from Gynura procumbens. Plant Foods fro Human Nutrition. 2002. 57, 233-244.
  6. Song, Y.; Coupar, I. M.; Iskander, M. N. Struction prediction of antagonist affinity at the adenosine 2B receptor site using molecular field analysis. Quant Struc.-Act. Relat. 2001. 20.

Consultancies

  • Cofounder and Director (Research), Cortical Pty. Ltd.