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Peter J. Scammells

Photo of Prof Scammells

Professor of Medicinal Chemistry

BSc, PhD (Griffith), MRACI CChem.

Phone: +61 3 9903 9614
Fax: +61 3 9903 9582
e-mail: Peter.Scammells@pharm.monash.edu.au

Research Interests

  • Antiarrhythmic agents based on adenosine
  • Allosteric enhancers of adenosine as cardioprotective agents
  • The design and synthesis of dual-acting antioxidants
  • Irreversible and bifunctional ligands for the study of drug receptor interactions
  • New syntheses of pharmaceutical opiates
  • Applications of ionic liquids in pharmaceutical synthesis
  • Design of biodegradable ionic liquids

Honours projects for 2008

Significant Publications

  1. T.D. Ashton, P.J. Scammells, An Expedient Synthesis of N6-Substituted-5'-Modified adenosines, Bioorg. Med. Chem. Lett. 2006, 16, 4564-4566.
  2. S. Thavaneswaran, P.J. Scammells, Further Investigation of the N-Demethylation of Tertiary Amine Alkaloids Using the Non-Classical Polonovski Reaction, Bioorg. Med. Chem. Lett. 2006, 16, 2868-2871.
  3. N. Gathergood, P.J. Scammells, M.T. Garcia, Biodegradable Ionic Liquids, Part III, Green Chem. 2006, 8, 156-160.
  4. G. Nikolakopoulos, J. Linden, H. Figler, P.J. Scammells, 2-Aminothiophene-3-carboxylates and Carboxamides as A1 Adenosine Receptor Allosteric Enhancers, Bioorg. Med. Chem. 2006, 14, 2358-2365.
  5. T.D. Ashton, P.J. Scammells, An Improved Synthesis of 5'-Fluoro-5'-deoxyadenosines, Bioorg. Med. Chem. Lett. 2005, 15, 3361-3363.
  6. S.A. Hutchinson, S.P. Baker, J.Linden, P.J. Scammells, New Potent and Selective A1 Adenosine Receptor Agonists, Bioorg. Med. Chem. Lett. 2004, 12, 4877-4884.
  7. S.A. Hutchinson, P.J. Scammells, A1 Adenosine Receptor Agonists: Medicinal Chemistry and Therapeutic Potential, Curr. Pharm. Design, 2004, 10, 2021-2039.
  8. K. McCamley, J.A. Ripper, R.D. Singer, P.J. Scammells, Efficient N-Demethylation of Opiate Alkaloids using a Modified Non-Classical Polonovski Reaction, J. Org. Chem. 2003, 68, 9847-9850.
  9. H. Lütjens, A. Zickgraf, H. Figler, J. Linden, R.A. Olsson, P.J. Scammells, 2-Amino-3-benzoylthiophene Allosteric Enhancers of A1 Adenosine Agonist Binding: New 3, 4- and 5-Modifications, J. Med. Chem. 2003, 46, 1870-1877.
  10. C.E. Tranberg, A. Zickgraf, B.N. Giunta, H. Lütjens, H. Figler, R. Falke, H. Fleischer, J. Linden, P.J. Scammells, R.A. Olsson, Amino-3-aroyl-4,5-dimethylthiophenes: Agonist Allosteric Enhancers at A1 Adenosine Receptors, J. Med. Chem. 2002, 45, 382-389.

Other Information

ARC Centre of Excellence of Free Radical Chemistry & Biotechnology - Management Commttee Member and CI. For more details please follow the link http://www.freeradical.org.au/