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Pharmaceutics - Facilities
Studies routinely conducted within the Department include analytical development, physicochemical characterisation, solid-state characterisation, solution microcalorimetry, stability monitoring, dissolution and particle size testing, preparation of lipid-based emulsions, in vitro permeability assessment, preclinical bioavailability and pharmacokinetic studies in small animals.
These areas are supported by:
Specialised equipment
- HPLC: gradient and isocratic systems, UV and fluorescence detectors
- High Performance Thin Layer Chromatography
- Liquid Chromatography-Mass Spectrometry (x2): liquid chromatograph interfaced to an orthogonal source API mass spectrometer with electrospray and APCI probes
- Gel and Capillary Electrophoresis Systems
- Circular Dichroism Spectropolarimeter
- FTIR Spectrometer
- UV and Fluorescence Spectrophotometers
- Laser Diffraction Particle Size Analyser
- Photon Correlation Spectrosometer
- Zetasizer
- Hot Stage Microscope with camera
- Thermal Analysis
- Differential Scanning Calorimeter
- Thermogravimetric Analyser
- Automated Dissolution Testing
- Karl Fischer Apparatus
- Tabletting, Spray Drying and Film Coating Equipment
- Microfluidizer: high pressure homogeniser for sub-micron emulsion preparation
- Microbalance: six figure balance with microgram accuracy
- Solution Microcalorimetry
- Milli-Q Ultra Purity Water Systems
- Osmometer
- Rheology: temperature controlled rotary viscometers
- Cone and Plate
- Rotating Cylinder
- Ultracentrifugation
- PCR Capability
- In Vitro Diffusion Chambers - Dedicated Permeability Research Suite
- Small Animal Surgical Facility
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