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Barrie C. Finnin

Professor of Formulation Science

Photo of Professor Barrie Finnin, Formulation Science
BPharm, VIC; PhD, Univ. Melbourne

Phone: +61 3 9903 9520
Fax: +61 3 9903 9583
email: Barrie.Finnin@pharm.monash.edu.au

General Research Interests

  • Transdermal Drug Delivery
  • Topical Drug Delivery
  • Mucosal Drug Delivery
  • Cosmeceuticals

Current Research Areas

  • Localisation of drugs during penetration through the skin
  • Mechanism of action of transdermal penetration enhancers
  • Drug uptake by the buccal mucosa

Significant Publications

  1. Nicolazzo, J.A., Finnin, B.C. In vivo and in vitro models for assessing drug absorption across the buccal mucosa. (2008) Biotechnology: Pharmaceutical Aspects. Drug Absorption studies, in situ, in vitro and in silico models, 89-111.
  2. Chew, N.Y.K., Reed, B.L., Morgan, T.M. and Finnin, B.C. Topical delivery of anti-fungal agents. (2006) US Patent Office 7094422
  3. Chew, N.Y.K., Reed, B.L., Morgan, T.M. and Finnin, B.C. Topical delivery of anti-alopecia agents. (2006) US Patent Office 6998138.
  4. Cilcott, R.P., Barai, N., Beezer, A.E., Brain, S.I., Brown, M.B., Bunge, A.L., Burgess, S.E., Cross, S., Dalton, C.H., Dias, A., Farinha, A., Finnin, B.C., Gallagher, S.J., Green, D.M, Gunt, H., Gwyther, R.L., Heard, C.M, Jarvis, C.A., Kamiyama, F., Kasting, G.B., Ley, E.E., Lim, S.T., Mcnaughton, G.S., Morris, A., Nazemi, M.H., Pellet, M.A., Du Plessis, J., Quan, Y.S., Raghavan, S.L., Roberts, M., Romonchuk, W., Roper, C.S., Schenk, D., Simonsen, L., Simpson, A., Traversa, B.D., Trottet, L., Watksinson, A., Wilkinson, S.C., Williams, F.M., Yamamoto, A., Hadgraft, J. Inter - and intralaboratory variation of in vitro diffusion cell measurements: An international and multicenter study using quasi-standardized methods and materials. (2005) Journal of Pharmaceutical Sciences 94(3): 632-638.
  5. Nicolazzo, J.A., Reed, B.L. and Finnin, B.C. Enhancing the buccal mucosal uptake and retention of triamcinolone acetonide. Journal of Controlled Release, 105: 240-248, 2005.
  6. Nicolazzo, J.A., Morgan, T.M., Reed, B.L. and Finnin, B.C. Synergistic enhancement of testosterone transdermal delivery. Journal of Controlled Release, 103: 577-585, 2005.
  7. Nicolazzo, J.A., Reed, B.L. and Finnin, B.C. Enhanced Buccal Mucosal Retention and Reduced Buccal Permeability of Estradiol in the presence pf Padimate O and Azone®: A Mechanistic Study. Journal of Pharmaceutical Sciences, 94(4): 873-882, 2005.
  8. Thomas, B.J. and Finnin, B.C. The transdermal revolution. Research Focus Reviews (9): 697-703 (2004) .
  9. Nicolazzo, J.A, Reed, B.L. and Finnin, B.C. "Modification of Buccal Drug Delivery Following pretreatment with Skin Penetration Enhancers".  J. Pharm.Sci., 8: 2064-2063,  2004.
  10. Nicolazzo, J.A, Reed, B.L. and Finnin, B.C. "An assessment of the effects of sodium dodecyl sulfate on the buccal permeability of caffeine and estradiol". J. Pharm. Sci., 93: 431-440, 2004
  11. Wolka, Anne M., Rytting, J.H Reed, B.L., and Finnin, B.C. The Interaction of the Penetration Enhancer DDAIP with a Phospholipid Model Membrane. Int. J. Pharm., 271: 5-10, 2004
  12. Nicolazzo, J.A, Reed B.L., and Finnin, B.C. "The effect of various in vitro conditions on the permeability characteristics of the buccal mucosa". J. Pharm. Sci., 92: 2399-2410, 2003
  13. Finnin, B.C.,  Morgan, T.M. Transdermal penetration enhancers: Application, limitations and potential. J. Pharm. Sci., 88: 955, 1999.
  14. Morgan, T.M., O'Sullivan, H.M.M.,  Reed, B.L. and Finnin, B.C. Transdermal delivery of estradiol in postmenopausal women with a novel topical aerosol. J. Pharm. Sci.87: 1226. 1998.
  15. Morgan, T.M.,  Reed, B.L. and Finnin B.C. Enhanced skin permeation of sex hormones with novel topical spray vehicles. J. Pharm. Sci.,, 87:1213, 1998.
  16. Tait, R.J., Bond A.M., Finnin, B.C., and  Reed, B.L. Rapid scanning voltammetry under steady-state conditions in a flow-through thin layer cell with a microelectrode. Collect. Czech. Chem. Comm.56: 92, 1991.
  17. Charman, W.N., Lai, C.S.C., Finnin B.C., and  Reed, B.L. Self association of nicotinamide in aqueous solution: Mass transport freezing point depression and partition coefficient studies. Pharm. Res., 8: 1144, 1991
  18. Dudinski, O., Finnin, B.C., and Reed, B.L. Acceptability of thickened eye drops to human subjects. Current Therapeutics Research33: 322, 1983.