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David A. V. Morton

Senior Lecturer in Formulation Science

BSc (Hons), Bristol; PhD, Univ. Bristol

Phone: +61 3 9903 9523
Fax: +61 3 9903 9583
email: david.morton@pharm.monash.edu.au

General Research Interests

  • Particle engineering in drug delivery
  • Control and study of surface properties of fine particles, and effects on behaviour and function
  • Understanding and improving formulation technology in inhalation systems

Current Research Areas

  • Controlling agglomerate structures in inhalation and dissolution delivery formats
  • Controlling multi-component particle formation processes during spray drying
  • Mechano-chemical bonding to coat fine particles: modified flow behaviour

Significant Publications

  1. Y. Kamlag and D.A.V. Morton. "Intelligent formulation by design: a case study for systematic delivery", 2006, Proceedings of Respiratory Drug Delivery 10, Florida, U.S.
  2. Y Kamlag, P. Kippax and D.A.V. Morton. "Uncovering the secrets of a dry powder inhaler plume". 2006, Proceedings of the Aerosol Society Drug Delivery to the Lungs XVII, Edinburgh, UK.
  3. P. Begat, D.A.V. Morton, R. Price and J.N. Staniforth. "The influence of force control agents on the adhesive-cohesive balance in dry powder inhaler formulations", 2005, KONA, 23, 109-121.
  4. P. Begat, D.A.V. Morton, R.Price and J.N. Staniforth. "The cohesive-adhesive balances in dry powder inhaler formulations I: direct quantification by atomic force microscope", 2004, Pharm. Res., 21, 1591-1597.
  5. P. Begat, D.A.V. Morton, R. Price and J.N. Staniforth. "The cohesive-adhesive balances in dry powder inhaler formulations II: influence of fine particle delivery characteristics", 2004, Pharm. Res., 21, 1826-1833.
  6. Q. Harmer, D.A. V. Morton, M. Newton, J.N. Staniforth and M. Tobyn. "Active and intelligent inhaler device development", 2004, Int. J. Pharmaceutics, 277, 31-37.
  7. R. M. Bannister, J.C. Gilbert, D.A.V. Morton, A.J.M. Richards and J.N. Staniforth. "Treatment of respiratory diseases", US patent US7229607, European Patent EP 1267866
  8. D.A.V. Morton, J.N Staniforth and I. G. McDerment. "Mouthpiece for a particulate inhaler", US Patent US6990974, European Patent EP1142601.
  9. D.A.V. Morton, D. Ganderton and P. Lucas. "Powders", US Patent US6989155, European Patent EP1137399.
  10. D.A.V. Morton, J.N. Staniforth and I.G. McDerment. "Mouthpiece for a particulate inhaler", US Patent US6810875, European Patent EP1163920.
  11. D.A.V. Morton. "Fire suppressant powder", US Patent US5938969.
  12. R. Bannister, H. Harris, D.A.V. Morton and J.N. Staniforth. "Method of preparing microparticles for use in pharmaceutical compositions for inhalation", European Patent EP1337241.
  13. D.A.V. Morton, J.N. Staniforth, R. Gill, G. Brambilla, L. Ferrarini and R. Musa. "Formulations for use in inhaler devices", European Patent EP1276472.
  14. D.A.V. Morton and J. N. Staniforth. "Formulations for use in inhaler devices", European Patent EP1276474.
  15. D.A.V. Morton. "Dry powder inhaler formulations comprising surface-modified particles with anti-adherent additives", Internal Patent Application WO2006/056812.
  16. D.A.V. Morton and J.N. Staniforth. "Dry powder compositions comprising co-jet milled particles for pulmonary inhalation", International Patent Application WO2005/025536.
  17. Y. Kamlag, D.A.V. Morton and J.N. Staniforth. "Improvements in spray-drying of a cohesive material for pulmonary delivery", 2004, Proceedings of Respiratory Drug Delivery 9, California, US.
  18. Q. Harmer and D.A.V. Morton. "Optimising device and formulation to regenerate primary particle distributions for systematic delivery", 2004, Proceedings of Respiratory Drug Delivery 9, California, US.
  19. P. Begat, D.A.V. Morton, R. Proce and J.N. Staniforth. "Investigation into the cohesive-adhesive force balance within a dry powder inhaler formulation", 2004, Proceedings of Respiratory Drug Delivery 9, California, US.
  20. P. Begat, P. Kippax, D.A.V. Morton, R, Proce and J.N. Staniforth. "The influence of force control agents on the aerosolisation properties of pharmaceutical drugs", 2004, Proceedings of Aerosol Society Drug Delivery to the Lungs XV, London, UK.
  21. H. Harris and D.A.V. Morton. "Powder dispersibility testing: the importance of optimising formulation to device", 2004, Proceedings of Aerosol Society Drug Delivery to the Lungs XV, London, UK.
  22. J. Conway, P. Conway, D.A.V. Morton, R. Proce, P. Smith and R. Summers. "E-Medic: linking informatics to a dry powder inhalation system", 2003, Proceedings of Aerosol Society Drug Delivery to the Lungs XIV, London, UK.
  23. P. Begat, M. Green, D.A.V. Morton, R. Price and J. N. Staniforth, A. Whittock and P. Young. "The study of force control additives in creating high-performance dry powder inhaler formulations", 2002, Proceedings of respiratory drug delivery 8, Arizona, US.
  24. P. Braithwaite, D. Ganderton, D.A.V. Morton, M. Parry-Billings, N. Patel, M Shott, J.N. Staniforth and M. Tservistas. "Biotech DPI Strategies: Accomplishing affordable control and effective action", 2002, Proceedings of Respiratory Drug Delivery 8, Arizona, US.
  25. D. Ganderton, D.A.V. Morton, D. Simpson and J.N. Staniforth. "Gas-phase aerosol synthesis of an additive material for enhancing dry powder inhaler formulation performance", 2002, Proceedings of Aerosol Society 13th Annual Conference, Lancaster, UK.
  26. S.A.R. Knox, B.R. Lloyd, D.A.V. Morton, A.G. Orpen and M.L. Turner. "Reactions of [Fe2(CO)6(µ-CO)(µ-dppm) with alkynes: step-wise synthesis of tropone at a dinuclear metal centre", 1995, Polyhedron, 14.