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Dr Ian C. Larson

Senior Lecturer in Pharmaceutics and Formulation Science

Picture of Dr Ian C. Larson
BSc(Hons), PhD, Univ. Melbourne

Phone: +61 3 9903 9570
Fax: +61 3 9903 9583
email: Ian.Larson@pharm.monash.edu.au

General Research Interests

  • Biopolymer drug delivery systems
  • Novel agricultural formulations
  • Dry particle behaviour and characterisation

Current Research Interests

  • Chitosan and pectin particles for colon specific delivery of hydrophilic macromolecules
  • Self micro-emulsifying delivery systems for the agricultural industry
  • Understanding the dispersion of micronised drugs for inhalation from powder mixtures using model mixtures
  • Quantifying the amorphous content of excipients using spectroscopic techniques

Significant Publications

  1. Adi, H., Larson, I.C. and Stewart, P.J. Use of milling and wet sieving to produce narrow particle size distributions of lactose monohydrate in the sub-sieve range (2007) Powder Technology 179 95-99.
  2. Adi, H., Larson, I.C. and Stewart, P.J.  Laser diffraction particle sizing of cohesive lactose powders (2007) Powder Technology 179 90-94.
  3. Das, S., Larson, I.C., Young, P. and Stewart, P.J.  The relationship between the performance and surface energy of salmeterol xinafoate powders for inhalation during long term storage at different relative humidity (2007) Proceedings of CHEMECA 2007: Academia and Industry Strengthening the Profession 468-474.
  4. Adi, H., Larson, I.C., Stewart, P.J.  Adhesion and redistribution of salmeterol xinafoate particles in sugar-based mixtures for inhalation (2007)  International Journal of Pharmaceutics 337 229-238.
  5. Dong, Y.D., Larson, I.C., Hanley, T. and Boyd, B.J.  Bulk dispersed aqueous phase behaviour of phytantriol: effect of vitamin E acetate and F127 polymer on liquid crystal nanostructure. (2006) Langmuir 22 9512-9518.
  6. Murphy, B.M., Prescott, S.W. and Larson, I.C. Measurement of lactose crystallinity using Raman spectroscopy (2005)  Journal of Pharmaceutical and Biomedical Analysis 38 186-190.
  7. Islam, N., Stewart, P.J., Larson, I.C. and Hartley, P. Surface roughness contribution of the adhesion force distribution of salmeterol xinafoate on lactose carriers by atomic force microscopy (2005) J Pharm Sci 94(7)1500-1511.
  8. Adi, H., Larson, I.C. and Stewart, P.J.  Influence of the particle size of fine lactose in the dispersion of salmetereol xinafoate from lactose mixtures for inhalation, (2004) Respiratory Drug Delivery IX  2553-556.
  9. Islam, N., Stewart, P.J., Larson, I. C. and Hartley, P. Lactose surface modification by decantation – are drug-fine lactose ratios the key to better dispersion of salmeterol xinafoate from lactose interactive mixtures? (2004) Pharm Res 21(3) 492-499.
  10. Islam, N., Stewart, P.J., Larson, I, Hartley, P. Effect of carrier size on the dispersion of Salmeterol Xinafoate from interactive mixtures. (2003). J Pharm. Sci 93(4)1030-1038.
  11. Larson, I. C. and Ralston, J. Atomic Force Microscopy and Colloid Interaction Forces in Encyclopaedia of Surface and Colloid Science (2002)  Marcel Dekker New York Ed: Hubbard, AJ.
  12. Larson, I. C. and Milling, A.J.  Electrical Double Layer Measurements using Atomic Force Microscopy in Surface Characterisation Methods: Principles, Techniques and Applications (1999)Marcel Dekker New York. Ed: Milling, AJ.
  13. Larson, I. C., Drummond, C.J., Chan, D.Y.C. and Grieser, F. Direct Force Measurements between TiO2 Surfaces.  (1993) J Am Chem Soc 115 11885–11890.