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Dr Ken Ng

Photo of Dr Ng

Lecturer

BSc(Hons), Monash University
PhD (Biochemistry), Monash University
Grad Cert in Higher Education, Monash University
Phone: +61 3 9903 9606
Fax: +61 3 9903 9583
email: Ken.Ng@pharm.monash.edu.au

General Research Interests

  • Antioxidants chemistry and delivery

Current Research Area

  • Free radical reactions of in vivo flavonoids metabolites and the nature of the antioxidant activities
  • Identification and quantification of antioxidants in food and medicinal herbs
  • Encapsulation of pharmacologically active antioxidants into nanoparticles as a mean to protect degradation in the gastro intestinal tract and to increase bioavailability to the body

 

Honours, Masters and PhD projects for 2008

Significant Publications

  1. T. Kogomotso, F. Chiu and K. Ng Genistein- and daidzein 7-O-b-D-glucuronic acid retain the ability to inhibit copper-mediated lipid oxidation of low density lipoprotein. Molecular Nutrition and Food Chemistry (In press)
  2. K. Le, F. Chiu and K.Ng. Identification and quantification of antioxidants. Fructus Lycii. Food Chemistry, 2007, 105, 353-363.
  3. B. Hsu,  I. Coupar and K. Ng . Antioxidant activity of hot water extract from the fruit of the Doum palm, Hyphaene thebaica.   Food Chemistry,2006,  98, 317-328.
  4. T. Igg, E. Handman, K. Ng, Y-D. Stierhof and A. Bacic. Mucin-like proteophosphoglycans from the protozoan parasite Leishmania. Trends In Glycoscience & Glycotechnology (Tokyo) Review, 1999, 11(58), 53-71. 
  5. N. B. Schwartz, S. Lyle, J. D. Orzeran, A. Deyrup, K. Ng and J. Westley. Sulfate activation and transport in mammals: system components and mechanism. Chemico-Biological Interactions, 1998, 109(1-3), 143-51.
  6. J. Menting, L. Tilley, L. Deady, K. Ng, R. J .Simpson, A .F. Cowman and M. Foley. The antimalarial drug chloroquine interacts with lactate dehydrogenase from Plasmodium falciparum. Molecular Biochemistry & Parasitology, 1998, 88, 215-24.
  7. K. Ng, E. Handman and A. Bacic. Biosynthesis of lipophosphoglycan from Leishmania Major: solubilization and purification of ß(1-3 )-galactosyltransferase.Biochemical Journal, 1996, 317, 247-55.
  8. K. Ng, E. Johnson and B. A. Stone. Specificity of binding of glucoside activator of rye grass Lolium multiflorum ß(1-3 )- glucan synthase and the synthesis of some potential photoaffinity activators. Plant Physiology, 1996, 111, 1227-31.
  9. A. Opat, K. Ng, G. Currie, E. Handman and A. Bacic. Characterisation of lipophosphoglycan from a ricin-resistant mutant from Leishmania major. Glycobiology, 1996, 6(4), 387-97.
  10. S. J. Rogerson, S. C. Chaiyaroy, K. Ng, J. C. Reader and G. V.Brown. Chondroitin-4-sulphate is a cell surface receptor for Plasmodium falciparum. Journal of Experimental Medicine, 1995, 182, 15-20.
  11. K. Ng, E. Handman and A. Bacic. Biosynthesis of lipophosphoglycan from Leishmania major: Characterisation of ß(1-3) galactosyltransferase. Glycobiology, 1994, 4, 845-53.
  12. M. Foley, L. Deady, K. Ng, A. Cowman and L. Tilley. Photoaffinity labelling of chloroquine-binding proteins in plasmodium falciparum. Journal of Biological Chemistry, 1994, 269(9), 6955-61.
  13. A. Berman, L. Shearing, K. Ng, M. Foley, W. Jinsart and L. Tilley. Photoaffinity labelling of Plasmodium falciparum proteins involved in phospholipid transport. Molecular & Biochemical Parasitology, 1994, 67, 235-43.
  14. S. Lyle, J. Stanczak, K. Ng and N. B. Schwartz. Rat chondrosarcoma ATP-sulphurylase and adenosine 5’-phosphosulphate kinase reside on a single bifunctional protein. Biochemistry, 1994, 33(19), 5920-25.
  15. S. Lyle, D. H. Geller, K. Ng, J. Westley and N. B. Schwartz. Kinetic mechanism of ATP-sulphurylase from rat chondrosarcoma. Biochemical Journal, 1994, 301, 349-54.
  16. S. Lyle, D. H. Geller, K. Ng, J. Stanczak, J. Westley and N. B. Schwartz. Kinetic mechanism of adenosine 5’-phosphosulphate kinase from rat chondrosarcoma. Biochemical Journal 1994, 301, 355-59.
  17. K. Illiama, T.B. Lam, J.P. Meikle, K. Ng, D. Rhodes and B.A. Stone. Cell wall biosynthesis and its regulation. Book: Proceedings of the International Symposium on Forage Cell Wall Structure and Digestibility (eds. Jung H., Buxton D., Hartfiled R. and Ralph J.), 1993, Chapter 24, 621-683.
  18. A. Beauvais, R. Drake, K. Ng, M. Diaquin and J. P. Latge. Characterization of the ß(1-3)-glucan synthase of Aspergillus fumigatus. Journal of General Microbiology, 1993, 139, 3071-78.
  19. P. J. Meikle, K. Ng, E. Johnson, N. J. Hoogenraad and B. A. Stone. The ß(1-3)-glucan synthase from Lolium multiforum: Detergent solubilisation, purification using monoclonal antibodies, and photoaffinity labelling with a novel photoaffinity analogue of uridine-5’-diphosphoglucose. Journal of Biological Chemistry, 1991, 266, 22569-581.
  20. K. Ng, M. D'Souza, D. H. Callahan, A. E. Kerns, S. Lyle and N. B. Schwartz. Synthesis and utilization of a non-hydrolysable phospoadenosine phosphosulphate analoge. Analytical Biochemistry, 1991, 198, 60-67.
  21. D. H. Callahan, N. B. Schwartz and K. Ng.  Dibasic amines as competitive ions improve the resolution between polyanionic nucleotides. Analytical Biochemistry, 1991, 196, 229-33.
  22. D. H. Callahan, K. Ng, D. H. Geller, K. Agarwal and  N. B. Schwartz.  Synthesis and properties of a non-hydrolysable adenosine phosphosulphate analogue. Analytical Biochemistry, 1989, 177, 67-71.
  23. K. Ng and  N. B. Schwartz. Solubilization and partial purification of hyaluronate synthase from oligodendroglioma cells. Journal of Biological Chemistry, 1989, 264, 1776-83.