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Prof Peter J. Stewart

Photo of Prof Stewart

Deputy Dean, Associate Dean (Teaching)

BPharm (Hon), PhD, Univ. Queensland

Phone: +61 3 9903 9517
Fax: +61 3 9903 9583
Email: Peter.Stewart@pharm.monash.edu.au

General Research Interests

  • Pharmaceutical formulation
  • Particle characterisation and adhesion
  • Dissolution of solid dosage forms

Current Research Interests

  • Improving the dispersion of micronised drugs for inhalation from powder mixtures
  • Understanding agglomeration and its role in the dissolution and dispersion of fine drugs
  • Formulation strategies to optimise dissolution of drugs
  • Research programs are in collaboration with Dr Ian Larson, Dr Patrick Hartley (Biomolecular Science, CSIRO), Associate Professor Kim Chan (University of Sydney) and Dr Robert Price (University of Bath)

Significant Publications

  1. Traini, D., Young, P., Chan, H.K., Stewart, P.J. and Adi, H. Co-sprayed dried antibiotics for dry powder inhalation delivery. (2007) Proceedings of Respiratory Drug Delivery 2007 Conference 369-372.
  2. Al Lahham, A. and Stewart, P.J. Enhancement of the dissolution of indomethacin in interactive mixtures using added fine lactose. (2007) European Journal of Pharmaceutics 67 732-742.
  3. Das, S., Larson, I.C., Young, P. and Stewart, P.J. The relationship between the performance and surface energy of salmeterol xinafoate powders for inhalation during long term storage at different relative humidity. (2007) Proceedings of CHEMECA 2007 Conference: Academia and Industry Strengthening the Profession 468-474.
  4. Kale, K., Hapgood, K. and Stewart, P.J. Effect of mixing speed and time on dispersion of cohesive drug powder mixtures measured during drug dissolution. (2007). Proceedings of CHEMECA 2007 Conference: Academia and Industry Strengthening the Profession 475-484.
  5. Adi, H., Larson, C. and Stewart, P.J. Use of milling and wet sieving to produce narrow particle size distributions of lactose monohydrate in the sub-sieve range. (2007) Powder Technology 179 95-99.
  6. Adi, H., Larson, I. C. and Stewart, P.J. Laser diffraction particle sizing of cohesive lactose powders. (2007) Powder Technology 17990-94.
  7. Adi, H., Larson, I.C. and Stewart, P.J. Adhesion and redistribution of salmeterol xinafoate particles in sugar-based mixtures for inhalation. (2007) International Journal of Pharmaceutics 337 229-238. 
  8. Stewart, P.J. The importance of 'fines' control in carrier lactose. (2006) Proceedings of the Respiratory Drug Delivery X Conference 333-342.
  9. Al Lahham, A., Stewart, P.J., Marriott, J. and Mainwaring, D. Factors Affecting Shear Thickening Behaviour of a Concentrated Injectable Suspension of Levodopa. (2005) J Pharm Sci 94(11) 2393-2402.
  10. Stewart, PJ and Zhao FY. Understanding agglomeration of indomethacin during the dissolution of micronised indomethacin mixtures through dissolution and de-agglomeration modelling approaches. (2005) European Journal of Pharmaceutics and Biopharmaceutics 59 315-323.
  11. Nazrul, I., Stewart, P.J., Larson, I.C. and Hartley, P. Surface roughness contribution to the adhesion force distribution of salmetereol xinafoate on lactose carriers by atomic force microscopy.(2005)  Journal of Pharmaceutical Sciences 94(7) 1500-1511.
  12. Islam, N., Stewart, P.J., Larson, I.C. and Hartley, P. Lactose surface modification by decantation – are drug-fine lactose ratios the key to better dispersion of salmeterol xinafoate from lactose interactive mixtures? (2004) Pharm Research 21(3) 492-499.
  13. Islam, N., Stewart P.J., Larson, I.C. and Hartley, P. The effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures. (2004) J Pharm Sci 93(4) 1030-1038.
  14. Zhao, F.Y., and Stewart, P.J. Modelling the De-agglomeration of Micronised Benzodiazepines from Powder Mixtures added to Dissolution Media. (2004) J Pharm Sci 93(6) 1618-1627.
  15. Louey, M.D., and Stewart, P.J. Particle interactions involved in aerosol dispersion of ternary interactive mixtures. (2002) Pharmaceutical Research 19 1524-1531.
  16. Louey, M.D., Mulvany, P. and Stewart, P.J. Characterisation of adhesional properties of lactose carriers using atomic force microscopy. (2001) Journal of Pharmaceutical and Biomedical Analysis 25559-567.
  17. Alway, B., Sangchantra, R. and Stewart, P,J. Modelling the dissolution of diazepam in lactose interactive mixtures. (1996) Int J Pharm 130  213-224.
  18. Kulvanich, P. and Stewart, P.J. The influence of relative humidity on the adhesive properties of a model interactive system. (1988) J Pharm Pharmacol 40453.
  19. Kulvanich, P. and  Stewart, P.J. Fundamental considerations in the measurement of adhesional forces between particles using the centrifuge method. (1987) Int J Pharm 35 111.