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David A. Taylor
Associate Professor
Associate Dean (Research Training)
BSc(Hons) University of Melbourne
PhD in Pharmacology University of Melbourne
Phone: +61 3 990 39568
Fax: +61 3 990 39638
email: David.Taylor@pharm.monash.edu.au
General Research Interests |
- Drugs effecting the central nervous system
- Drugs of abuse
- Neurotransmitters
- Antidepressants
Current Research Areas
- The effects of cannabinoids, cocaine and morphine
- The interaction between 5-hydroxytryptamine and dopamine in the brain
- Potential antipsychotic drugs
- The neurotransmitters involved in controlling appetite
- Neurotransmitters involved in reward processes
Significant Publications
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Nielsen, S., Dietze, P., Cantwell, K., Lee, N. & Taylor, D.A. (2008) Methadone and Buprenorphine related ambulance attendances: A population-based indicator of adverse events. Journal of Substance Abuse Treatment, in press.
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Capuano, B.,Crosby, I.T., Lloyd, E.J., Neve, J.E. & Taylor, D.A. (2008) Aminimides as Potential CNS Acting Agents. II. Design, Synthesis and Receptor Binding of 4'-Arylalkyl Aminimide Analogues of Clozapine as Prospective Novel Antipsychotics. Australian Journal of Chemistry, 61, 5-10.
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Malone, D.T., Kearn, C.S., Lily Chongue, L., Mackie, K. and Taylor, D.A. (2008) Effect of social isolation on CB1 and D2 receptor and fatty acid amide hydrolase expression in rats. Neuroscience, 152, 265-272.
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Capuano, B., Crosby, I.T., Lloyd, E.J., Neve, J.E. & Taylor, D.A. (2008) Aminimides as potential CNS-acting agents. III. Design, synthesis, and receptor binding of aminimide analogues of dopamine, serotonin, morphine, and nicotine. Australian Journal of Chemistry, 61, 422-431.
- Capuano, B., Crosby, I.T., Lloyd, E.J., Neve, J.E. & Taylor, D.A. (2007) Aminimides as Potential CNS Acting Agents. I. Design, Synthesis and Receptor Binding of 4'-Aryl Aminimide Analogues of Clozapine as Prospective Novel Antipsychotics. Australian Journal of Chemistry, 60, 673-684.
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Jazayeri, J.A., deWeerd, N., Raye, W., Santos, L., Taylor , D.A. & Carroll, G.J. (2007) Generation of mutant leukaemia inhibitory factor (LIF)-IgG heavy chain fusion proteins as bivalent antagonists of LIF. Journal of Immunological Methods, 323, 1-10.
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Nielsen, S., Dietze, P., Dunlop, A., Muhleisen, P., Lee, N. & Taylor, D.A. (2007) Buprenorphine Supply by Community Pharmacists in Victoria, Australia: Perceptions, Experiences and Key Issues IdentifiedDrug and Alcohol Review, 26, 143-151.
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Nielson, S., Dietze, P., Lee, N., Dunlop, A. & Taylor, D.A. (2007) Concurrent buprenorphine and benzodiazepines use and self-reported opioid toxicity in opioid substitution treatment, Addiction, 102, 616-622.
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Capuano, B., Crosby, I.T., Lloyd, E.J., & Taylor, D.A. (2007) Synthesis and Preliminary Pharmacological Evaluation of 4'‑Arylalkyl Analogues of Clozapine. III. Replacement of the Tricyclic Nucleus with a Bicyclic Template. Australian Journal of Chemistry, 60, 928-933.
- Malone D.T. and Taylor D.A. (2006) The effect of tetrahydrocannabinol on sensorimotor gating in socially isolated rats. Behav Brain Res. 166(1):101-9.
- Long L.E., Malone D.T. and Taylor D.A. (2006) Cannabidiol reverses MK-801-induced disruption of prepulse inhibition in mice. Neuropsychopharmacology31(4):795-803 (published online 2005).
- Long L.E. Malone D.T., and Taylor D.A. (2005) The pharmacological actions of cannabidiol. Drugs of the Future, 30(7): 747-753.
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Nielsen, S., Muhleisen, P., Taylor, D., Dunlop, A., Dietze, P. & Lee N. (2005) Preliminary findings on concurrent buprenorphine and benzodiazepine use in Victoria. Australian Pharmacist, 24, 488-489.
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Nielsen, S. & Taylor, D.A. (2005) The effect of buprenorphine and benzodiazepines on respiration in the rat. Drug and Alcohol Dependence, 79, 95-101.
- Malone D.T., Long L.E. & Taylor D.A. (2004) The effect of SR 141716 and apomorphine on sensorimotor gating in Swiss mice. Pharmacology, Biochemistry and Behavior 77/4: 839-845.
- Capuano, B., Crosby, I.T., Lloyd, E.J. & Taylor, D.A. (2003) Synthesis and preliminary pharmacological evaluation of 4¢-arylmethyl analogues of Clozapine. II. Effect of the Nature and Length of the Linker. Australian Journal of Chemistry, 56, 875-886.
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