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Sab Ventura

Photo of Dr Ventura

Senior Lecturer

BSc(Hons) Monash University
PhD in Pharmacology Monash University

Phone: +61 3 990 39566
Fax:     +61 3 990 39638
email: Sab.Ventura@pharm.monash.edu.au

General Research Interests

  • Neurotransmission to the male reproductive organs
  • Peripheral sympathetic cotransmission
  • Immunohistochemistry of male reproductive organs

Current Research Areas

  • Pharmacology of neurotransmission in the prostate gland
  • Immunohistochemistry of the prostate gland
  • Pharmacology of drugs that relax the prostate gland

Significant Publications

  1. Gray K.T., Short J.L. & VenturaS. (2008) The a1A-adrenoceptor gene is required for the a1L-adrenoceptor-mediated response in isolated preparations of the mouse prostate.  British Journal of Pharmacology 155: 103-109.
  2. Gray K.T., Short J.L., Ledent C. & Ventura S. (2008) Targeted disruption of the A2A adenosine receptor reduces in vitro prostate contractility in mature mice.  European Journal of Pharmacology 592: 151-157.
  3. Gray K.T., Short J.L., Simpson E. & Ventura S.  (2007) The effects of targeted deletion of the aromatase enzyme on prostatic contractile responses to noradrenaline in mice.  Journal of Endocrinology; 195: 495-502.
  4. Tokanovic S., Malone D.T. & Ventura S.  (2007)  Stimulation of epithelial CB1 receptors inhibits contractions of the rat prostate gland.  British Journal of Pharmacology 150: 227-234.
  5. Gray K.T. and Ventura S. (2006) a1L-Adrenoceptors mediate contractions of the isolated mouse prostate.  European Journal of Pharmacology; 540: 155-161.
  6. Cao N., Haynes J.M. & Ventura S.  (2006) Saw palmetto is an indirectly acting sympathomimetic in the rat isolated prostate gland.  Prostate; 66: 115-123.
  7. Gray K.T. & Ventura S.  (2005) Evaluation of the mouse prostate as a suitable model for the study of human prostate function.  Journal of Pharmacological and Toxicological Methods; 51: 41-50.
  8. Haynes J.M. & Ventura S.  (2005) Current models of human prostate contractility.  Clinical and Experimental Pharmacology and Physiology; 32: 797-804.
  9. Buljubasich R. and Ventura S. (2004) Adenosine 5’-triphosphate (ATP) and noradrenaline are excitatory cotransmitters to the fibromuscular stroma of the guinea-pig prostate gland.  Eur. J. Pharmacol. 499: 335-344
  10. Ventura S., Dewalagama R.K. and Lau L.C.L. (2003) Adenosine 5'-triphosphate (ATP) is an excitatory cotransmitter with noradrenaline to the smooth muscle of the rat prostate gland. Br. J. Pharmacol. 138: 1277-1284
  11. Ventura S., Pennefather J.N. and Mitchelson F.J. (2002) Cholinergic innervation and function in the prostate gland. Pharmacol. Ther. 94: 93-112
  12. Ramasamy S., Hodgson W.C. and Ventura S. (2002) Protein kinase C and the sub-sensitivity and sub-reactivity of the diabetic rat prostate gland to noradrenaline. Eur. J. Pharmacol. 434: 151-161
  13. Ventura S. and Salamoussa A. (2002) Big endothelin-1 but not endothelin-1 is present in the smooth muscle stroma of the prostate gland of the rat. J. Anat. 200: 153-158
  14. Kalodimos P.J. and Ventura S. (2001) b2-adrenoceptor mediated inhibition of field stimulation induced contractile responses of the smooth muscle of the rat prostate gland. Eur. J. Pharmacol. 431: 81-89
  15. Pennefather J.N., Lau, W.A.K., Mitchelson F.J. and Ventura S. (2000) The autonomic and sensory innervation of the smooth muscle of the prostate gland: a review of pharmacological and histological studies. J. Auton. Pharmacol. 20: 193-206
  16. Ventura S., Lau, W.A.K., Buljubasich S. and Pennefather J.N. (2000) Species differences in the actions of sensory neuropeptides on contractility of the smooth muscle of the rat and guinea-pig prostate. Clin. Exp. Pharmacol. Physiol. 27: 917-921
  17. Preston A., Lau W.A.K., Pennefather J.N. and Ventura S. (2000) Effects of adenine nucleosides and nucleotides on neuromuscular transmission to the prostatic stroma of the rat. Br. J. Pharmacol. 131: 1073-1080
  18. Salamoussa A., Lau W.A.K., Pennefather J.N. and Ventura S. (2000) The contractile effects of endothelin on the smooth muscle of the rat prostate gland. Eur. J. Pharmacol. 403: 139-145
  19. Ventura S., Lau W.A.K., Buljubasich S. and Pennefather J.N. (2000) Calcitonin gene-related peptide (CGRP) inhibits contractions of the prostatic stroma of the rat but not the guinea-pig. Reg. Pept. 91: 63-73